AA-WGAN: Attention augmented Wasserstein generative adversarial network with application to fundus retinal vessel segmentation. (May 2023)

• Record Type: Journal Article
• Authors: Liu, Meilin; Wang, Zidong; Li, Han; Wu, Peishu; Alsaadi, Fuad E.; Zeng, Nianyin
• Is Part Of: Computers in biology and medicine. Volume 158(2023)
• Publication Date: 2023-05
• Subjects: Artificial intelligence -- Generative adversarial network (GAN) -- Attention mechanism -- Vessel segmentation -- Imperfect data; Medicine -- Data processing -- Periodicals; Biology -- Data processing -- Periodicals; 610.285
• DOI: 10.1016/j.compbiomed.2023.106874
• Languages: English
• ISSNs: 0010-4825

Abstract

Abstract: In this paper, a novel attention augmented Wasserstein generative adversarial network (AA-WGAN) is proposed for fundus retinal vessel segmentation, where a U-shaped network with attention augmented convolution and squeeze-excitation module is designed to serve as the generator. In particular, the complex vascular structures make some tiny vessels hard to segment, while the proposed AA-WGAN can effectively handle such imperfect data property, which is competent in capturing the dependency among pixels in the whole image to highlight the regions of interests via the applied attention augmented convolution. By applying the squeeze-excitation module, the generator is able to pay attention to the important channels of the feature maps, and the useless information can be suppressed as well. In addition, gradient penalty method is adopted in the WGAN backbone to alleviate the phenomenon of generating large amounts of repeated images due to excessive concentration on accuracy. The proposed model is comprehensively evaluated on three datasets DRIVE, STARE, and CHASE_DB1, and the results show that the proposed AA-WGAN is a competitive vessel segmentation model as compared with several other advanced models, which obtains the accuracy of 96.51%, 97.19% and 96.94% on each dataset, respectively. The effectiveness of the applied important components is validated by ablation study, which also endows the proposed AA-WGAN with considerable generalization ability. Highlights: The combination of ASU-Net and WGAN promotes accurate segmentation. The global feature extraction ability is enhanced by the designed ASU-Net. AugConv module and SE block improve the model generalization ability and robustness.