Inactivation of nontuberculous mycobacteria by gaseous ozone treatment. Issue 6 (June 2023)

• Record Type: Journal Article
• Authors: Misawa, Kana; Nishimura, Tomoyasu; Kashimura, Shoko; Hasegawa, Naoki
• Is Part Of: Journal of infection and chemotherapy. Volume 29:Issue 6(2023)
• Page Start: 628
• Page End: 630
• Publication Date: 2023-06
• Subjects: Nontuberculous mycobacteria -- Gaseous ozone -- Disinfection; Chemotherapy -- Periodicals; Infection -- Periodicals; Communicable diseases -- Chemotherapy -- Periodicals; 615.5805
• DOI: 10.1016/j.jiac.2023.03.004
• Languages: English
• ISSNs: 1341-321X

Abstract

Abstract: Nontuberculous mycobacteria (NTM) are environmental bacteria resistant to many common disinfectants and ultraviolet radiation. Inhalation of aerosols generated from NTM-containing water and soil causes NTM lung disease, especially in people with underlying lung diseases and decreased immunity. To prevent healthcare-acquired NTM infections, it is important to eradicate NTM living in hospital environments. Therefore, we evaluated the efficacy of gaseous ozone for the inactivation of NTM, namely Mycobacterium ( M. ) avium, M. intracellulare, M. kansasii, M. abscessus subsp. abscessus and M. abscessus subsp. massiliense. Gaseous ozone treatment at 1 ppm for 3 h reduced the bacterial number of all strains by more than 97%. Gaseous ozone treatment could be a practical, effective and convenient disinfection method for NTM living in hospital environments.