Inside Back Cover: Salt Metathesis: Tetrafluoroborate Anion Rapidly Fluoridates Organoboronic Acids to give Organotrifluoroborates (Angew. Chem. Int. Ed. 16/2023). Issue 16 (15th March 2023)

• Record Type: Journal Article
• Authors: Lozada, Jerome; Xuan Lin, Wen; Cao‐Shen, Rosana M.; Astoria Tai, Ruyin; Perrin, David M.
• Is Part Of: Angewandte Chemie international edition. Volume 62:Issue 16(2023)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2023-03-15
• Subjects: Fluoridation -- Methoxytrifluoroborate -- Salt Metathesis -- Synthetic Method -- Tetrafluoroborate; Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.202303376
• Languages: English
• ISSNs: 1433-7851

Abstract

Abstract : Salt metathesis and BFX (boron–fluoride exchange) of BF4 − with boronic acids generates RBF3 − derivatives, thus showing the solvolytic lability of BF4 − that enables its use as a fluorinating agent, even though many highly reactive reagents employ BF4 − as a non‐reactive counteranion. In their Research Article (e202215371), David M. Perrin and co‐workers report the synthesis of RBF3 − derivatives via a salt metathesis reaction using a series of MBF4 salts in methanol. This work highlights the proclivity of BF4 −, generally considered weakly coordinating and unreactive, to rapidly fluorinate boronic acids.