The role of female intimate hygiene practices in the management of vulvovaginal candidiasis: A randomized, controlled open-label trial. Issue 5 (4th May 2023)

• Record Type: Journal Article
• Authors: Murina, Filippo; Lubrano, Chiara; Cappelli, Elisa; Campo, Maria; Taraborrelli, Stefania
• Is Part Of: Health care for women international. Volume 44:Issue 5(2023)
• Page Start: 689
• Page End: 700
• Publication Date: 2023-05-04
• Subjects: Women -- Health and hygiene -- Periodicals; Women's health services -- Periodicals; Genital Diseases, Female; Neonatology; Obstetrics; Women -- psychology; Femmes -- Santé et hygiène -- Périodiques; Femmes -- Santé, Services de -- Périodiques; 613.0424405
• DOI: 10.1080/07399332.2022.2061972
• Languages: English
• ISSNs: 0739-9332

Abstract

Abstract: In this multicenter, observational, controlled open-label trial, researchers randomized 200 women with vulvovaginal candidiasis (VVC) to: Group 1, 6-days clotrimazole 2% vaginal cream once-daily plus 15-days concomitant acid pH thymol and zinc-containing cleansing wash (SaugellaActi3) twice-daily; Group 2, 6-days clotrimazole treatment alone. In both groups, pruritus and burning VAS scores improved from baseline at Days 6, 10 and 15. On Day 10 and Day 15, the pruritus score was significantly lower in Group 1 versus Group 2 ( P <0.005 at both timepoints), suggesting acid pH thymol and zinc-containing cleansing wash ameliorates VVC-associated pruritus as part of a female hygiene regimen.