Method considerations and study protocol for a Nordic multi‐centre prospective study on outcomes in rare paediatric epilepsy surgery subgroups. (8th February 2023)

• Record Type: Journal Article
• Authors: Reinholdson, Jesper; Malmgren, Kristina; Chaplin, John; Olsson, Ingrid; Hallböök, Tove
• Is Part Of: Acta pædiatrica. Volume 112:Number 5(2023)
• Page Start: 924
• Page End: 930
• Publication Date: 2023-02-08
• Subjects: Pediatrics -- Periodicals; Pediatrics; 618.92
• DOI: 10.1111/apa.16691
• Languages: English
• ISSNs: 0803-5253

Abstract

Abstract: Epilepsy surgery is a therapeutic option for selected children with drug‐resistant epilepsy. Children who are surgical candidates have a high prevalence of neurodevelopmental comorbidities. There is a lack of adequately sized prospective studies in a number of rare surgical subgroups, especially of outcome domains such as cognitive level and health‐related quality‐of‐life. In this article, we describe method considerations and a study protocol for a Nordic population‐based multi‐centre follow‐up programme covering seizure as well as non‐seizure outcomes in children aged <4 years undergoing resective epilepsy surgery and children aged ≤18 years undergoing hemispherotomy, callosotomy or surgery for hypothalamic hamartoma.