Neurodegeneration in Hepatic and Neurologic Wilson's Disease. Issue 2 (6th May 2021)

• Record Type: Journal Article
• Authors: Viveiros, André; Beliveau, Vincent; Panzer, Marlene; Schaefer, Benedikt; Glodny, Bernhard; Henninger, Benjamin; Tilg, Herbert; Zoller, Heinz; Scherfler, Christoph
• Is Part Of: Hepatology. Volume 74:Issue 2(2021)
• Page Start: 1117
• Page End: 1120
• Publication Date: 2021-05-06
• Subjects: Heart -- Diseases -- Nursing -- Periodicals; Lungs -- Diseases -- Nursing -- Periodicals; Intensive care nursing -- Periodicals; Foie -- Maladies -- Périodiques; 616.362
• DOI: 10.1002/hep.31681
• Languages: English
• ISSNs: 0270-9139

Abstract

Abstract : Clinical presentation of Wilson disease (WD) includes hepatic and neurologic manifestations. This study compares subcortical brain regions by magnetic resonance imaging in patients with WD and without neurological symptoms. Distinct atrophy affecting the basal ganglia, accumbens, and hippocampus was present in neurological WD. Cerebellar atrophy was observed in hepatic WD without neurological symptoms.