Acute kidney injury in cardiogenic shock: A comprehensive review. Issue 1 (29th July 2020)

• Record Type: Journal Article
• Authors: Sheikh, Omar; Nguyen, Tung; Bansal, Shweta; Prasad, Anand
• Is Part Of: Catheterization and cardiovascular interventions. Volume 98:Issue 1(2021)
• Page Start: E91
• Page End: E105
• Publication Date: 2020-07-29
• Subjects: cardiorenal syndrome -- mechanical support -- myocardial infarction -- renal replacement therapy; Heart -- Diseases -- Diagnosis -- Periodicals; Cardiac catheterization -- Periodicals; 616.1207572
• DOI: 10.1002/ccd.29141
• Languages: English
• ISSNs: 1522-1946

Abstract

Abstract: Acute kidney injury (AKI) is an ominous predictor of mortality in cardiogenic shock. The present review examines the pathophysiology of AKI in cardiogenic shock (CS), summarizes the pertinent literature including the diagnostic criteria/definitions for AKI and possible role of biomarkers, and identifies risk factors and possible therapeutic interventions for AKI in CS. Our review finds that AKI is common in patients with CS and is associated with increased morbidity and mortality. Urinary biomarkers of renal tubular injury appear more sensitive for detection of AKI but have yet to be incorporated into daily practice. Emerging data would suggest vasopressor choices, mechanical circulatory support, and renal replacement therapy may have important therapeutic roles in the management of CS.