Application of gold nanoparticles in biomedical and drug delivery. (2nd January 2016)

• Record Type: Journal Article
• Authors: Daraee, Hadis; Eatemadi, Ali; Abbasi, Elham; Fekri Aval, Sedigheh; Kouhi, Mohammad; Akbarzadeh, Abolfazl
• Is Part Of: Artificial cells, nanomedicine, and biotechnology. Volume 44:Number 1(2016)
• Page Start: 410
• Page End: 422
• Publication Date: 2016-01-02
• Subjects: biocompatible -- drug delivery -- gold nanoparticle -- immunoassay -- photothermal; Artificial cells -- Periodicals; Nanotechnology -- Periodicals; Blood substitutes -- Periodicals; Tissue engineering -- Periodicals; Molecules -- Periodicals; Biotechnology -- Periodicals; 615.39
• DOI: 10.3109/21691401.2014.955107
• Languages: English
• ISSNs: 2169-1401

Abstract

Abstract : Nanoparticles are the simplest form of structures with sizes in the nanometer (nm) range. In principle any collection of atoms bonded together with a structural radius of < 100 nm can be considered nano particles. Nanotechnology offers unique approaches to probe and control a variety of biological and medical processes that occur at nanometer scales, and is expected to have a revolutionary impact on biology and medicine. Among the approaches for exploiting nanotechnology in medicine, nanoparticles offer some unique advantages as sensing, image enhancement, and delivery agents. Several varieties of nanoparticles with biomedical relevance are available including, polymeric nanoparticles, metal nanoparticles, liposomes, micelles, quantum dots, dendrimers, and nanoassemblies. To further the application of nanoparticles in disease diagnosis and therapy, it is important that the systems are biocompatible and capable of being functionalized for recognition of specific target sites in the body after systemic administration. In this review, we have explained some important applications of gold nanoparticles.