An update on clinical applications of magnetic nanoparticles for increasing the resolution of magnetic resonance imaging. (2nd October 2016)

• Record Type: Journal Article
• Authors: Zeinali Sehrig, Fatemeh; Majidi, Sima; Asvadi, Sahar; Hsanzadeh, Arash; Rasta, Seyed Hossein; Emamverdy, Masumeh; Akbarzadeh, Jamshid; Jahangiri, Sahar; Farahkhiz, Shahrzad; Akbarzadeh, Abolfazl
• Is Part Of: Artificial cells, nanomedicine, and biotechnology. Volume 44:Number 7(2016)
• Page Start: 1583
• Page End: 1588
• Publication Date: 2016-10-02
• Subjects: Diagnostic applications -- gadolinium -- magnetic nanoparticles -- magnetic resonance imaging; Artificial cells -- Periodicals; Nanotechnology -- Periodicals; Blood substitutes -- Periodicals; Tissue engineering -- Periodicals; Molecules -- Periodicals; Biotechnology -- Periodicals; 615.39
• DOI: 10.3109/21691401.2015.1101001
• Languages: English
• ISSNs: 2169-1401

Abstract

Abstract: Today, technologies based on magnetic nanoparticles (MNPs) are regularly applied to biological systems with diagnostic or therapeutic aims. Nanoparticles made of the elements iron (Fe), gadolinium (Gd) or manganese (Mn) are generally used in many diagnostic applications performed under magnetic resonance imaging (MRI). Similar to molecular-based contrast agents, nanoparticles can be used to increase the resolution of imaging while offering well biocompatibility, poisonousness and biodistribution. Application of MNPs enhanced MRI sensitivity due to the accumulation of iron in the liver caused by discriminating action of the hepatobiliary system. The aim of this study is about the use, properties and advantages of MNPs in MRI.