PIK3CA-related overgrowth: silver bullets from the cancer arsenal?. Issue 4 (April 2022)
- Record Type:
- Journal Article
- Title:
- PIK3CA-related overgrowth: silver bullets from the cancer arsenal?. Issue 4 (April 2022)
- Main Title:
- PIK3CA-related overgrowth: silver bullets from the cancer arsenal?
- Authors:
- Madsen, Ralitsa R.
Semple, Robert K. - Abstract:
- Abstract : Mutations that activate growth factor signaling often drive cancer growth. Many also arise in isolation, causing developmental growth disorders. PIK3CA, that encodes a catalytic subunit of phosphatidylinositol 3-kinase (PI3K), is a cardinal example of this paradigm. Recent exciting progress towards the key goal of cancer drug repurposing for PIK3CA-driven overgrowth is discussed.
- Is Part Of:
- Trends in molecular medicine. Volume 28:Issue 4(2022)
- Journal:
- Trends in molecular medicine
- Issue:
- Volume 28:Issue 4(2022)
- Issue Display:
- Volume 28, Issue 4 (2022)
- Year:
- 2022
- Volume:
- 28
- Issue:
- 4
- Issue Sort Value:
- 2022-0028-0004-0000
- Page Start:
- 255
- Page End:
- 257
- Publication Date:
- 2022-04
- Subjects:
- PROS -- PIK3CA -- overgrowth -- CLOVES -- PI3K -- phosphatidylinositol 3-kinase -- alpelisib -- sirolimus -- trials
Molecular biology -- Periodicals
Pathology, Molecular -- Periodicals
Physiology, Pathological -- Periodicals
572.8 - Journal URLs:
- http://www.sciencedirect.com/science/journal/14714914 ↗
http://www.elsevier.com/locate/issn/14714914 ↗
http://www.clinicalkey.com/dura/browse/journalIssue/14714914 ↗
http://www.clinicalkey.com.au/dura/browse/journalIssue/14714914 ↗
http://www.elsevier.com/journals ↗ - DOI:
- 10.1016/j.molmed.2022.02.009 ↗
- Languages:
- English
- ISSNs:
- 1471-4914
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 9049.666000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 26866.xml