Role of growth factors and biomaterials in wound healing. (31st October 2018)

• Record Type: Journal Article
• Authors: Zarei, Farshad; Soleimaninejad, Maryam
• Is Part Of: Artificial cells, nanomedicine, and biotechnology. Volume 46(2018)Supplement 1
• Page Start: 906
• Page End: 911
• Publication Date: 2018-10-31
• Subjects: Wound healing -- stem cells -- biomaterials -- growth factors -- wound repair; Artificial cells -- Periodicals; Nanotechnology -- Periodicals; Blood substitutes -- Periodicals; Tissue engineering -- Periodicals; Molecules -- Periodicals; Biotechnology -- Periodicals; 615.39
• DOI: 10.1080/21691401.2018.1439836
• Languages: English
• ISSNs: 2169-1401

Abstract

Abstract: Wound healing is a biological complex process that involves several cell types under the control and regulation of several growth factors and cytokines. There have been efforts to study the therapeutic effects of granulocyte-macrophage colony-stimulating factor, platelet-derived growth factor, transforming growth factor-β, vascular endothelial growth factor and basic fibroblast growth factor on chronic wounds. In addition, the effects of biomaterials such as nano-fibrous chitin and chitosan have been proven to be effective on wound healing. Furthermore, stem cell therapy using adipose-derived stem cells (ASCs) has been developed as a new therapeutic method for wound repair and healing. In this review, we will summarize the role of stem cells; growth factors and biomaterials in wound healing and repair.