Design, synthesis of 10-alkoxy-5-spiro CPT and preliminary biological evaluation in vitro. (6th April 2023)
- Record Type:
- Journal Article
- Title:
- Design, synthesis of 10-alkoxy-5-spiro CPT and preliminary biological evaluation in vitro. (6th April 2023)
- Main Title:
- Design, synthesis of 10-alkoxy-5-spiro CPT and preliminary biological evaluation in vitro
- Authors:
- Ke, Xi
Wang, Xianheng
Liu, Yuan
Wang, Yuhe
Zhao, Changkuo - Abstract:
- Abstract: A series of 10-alkoxy-5-spirocycle campthothecin derivatives were synthesized in a convenient method. On the one hand, the solubility of these compounds was obviously modified; on the other hand, most of these 5-spirocycle campthothecin derivatives showed a better inhibition activity against MGC803 cell line. Graphical abstract: Image 1
- Is Part Of:
- Tetrahedron. Volume 135(2023)
- Journal:
- Tetrahedron
- Issue:
- Volume 135(2023)
- Issue Display:
- Volume 135, Issue 2023 (2023)
- Year:
- 2023
- Volume:
- 135
- Issue:
- 2023
- Issue Sort Value:
- 2023-0135-2023-0000
- Page Start:
- Page End:
- Publication Date:
- 2023-04-06
- Subjects:
- Campthothecin -- Spirocycle -- Cyclization -- Anticancer -- In vitro
Chemistry, Organic -- Periodicals
547.005 - Journal URLs:
- http://www.elsevier.com/journals ↗
- DOI:
- 10.1016/j.tet.2023.133325 ↗
- Languages:
- English
- ISSNs:
- 0040-4020
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 8796.850000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 26876.xml