Dipeptidyl Peptidase 4/Midline‐1 Axis Promotes T Lymphocyte Motility in Atherosclerosis (Adv. Sci. 9/2023). Issue 9 (24th March 2023)

• Record Type: Journal Article
• Authors: Rao, Xiaoquan; Razavi, Michael; Mihai, Georgeta; Wei, Yingying; Braunstein, Zachary; Frieman, Matthew B.; Sun, Xiao Jian; Gong, Quan; Chen, Jun; Zhao, Gang; Liu, Zheng; Quon, Michael J.; Dong, Lingli; Rajagopalan, Sanjay; Zhong, Jixin
• Is Part Of: Advanced science. Volume 10:Issue 9(2023)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2023-03-24
• Subjects: Science -- Periodicals; 505
• DOI: 10.1002/advs.202370049
• Languages: English
• ISSNs: 2198-3844

Abstract

Abstract : Atherosclerosis T lymphocyte infiltration in the plaque is a crucial process of atherosclerosis development. In article number 2204194, Jixin Zhong and co‐workers report a novel mechanism regulating the migration of T lymphocytes to the atherosclerotic lesions. This study not only fills a knowledge gap in our understanding of the pathogenesis of atherosclerosis, but also provides a new therapeutic target for vascular inflammation.