Recent advances in biomimetic hemostatic materials. (April 2023)

• Record Type: Journal Article
• Authors: Jiao, Simin; Zhang, Xi; Cai, Hang; Wu, Siyu; Ou, Xiaolan; Han, Guangda; Zhao, Jie; Li, Yan; Guo, Wenlai; Liu, Tianzhou; Qu, Wenrui
• Is Part Of: Materials today bio. Volume 19(2023)
• Publication Date: 2023-04
• Subjects: Biomimetic materials -- Hemostasis -- Adhesion; Materials science -- Periodicals; Biomedical engineering -- Periodicals; Biomedical materials -- Periodicals; 620.1
• DOI: 10.1016/j.mtbio.2023.100592
• Languages: English
• ISSNs: 2590-0064

Abstract

Abstract: Although the past decade has witnessed unprecedented medical advances, achieving rapid and effective hemostasis remains challenging. Uncontrolled bleeding and wound infections continue to plague healthcare providers, increasing the risk of death. Various types of hemostatic materials are nowadays used during clinical practice but have many limitations, including poor biocompatibility, toxicity and biodegradability. Recently, there has been a burgeoning interest in organisms that stick to objects or produce sticky substances. Indeed, applying biological adhesion properties to hemostatic materials remains an interesting approach. This paper reviews the biological behavior, bionics, and mechanisms related to hemostasis. Furthermore, this paper covers the benefits, challenges and prospects of biomimetic hemostatic materials. Graphical abstract: Image 1 Highlights: The biological model related to hemostasis is first elucidated. The bionic principle and hemostatic mechanism of bionic hemostatic materials are introduced. The latest development and future research direction of biomimetic hemostatic materials are discussed.