A salicylaldoximate-based AIE probe for the detection of the nerve agent simulant DCP. Issue 12 (13th March 2023)

• Record Type: Journal Article
• Authors: Li, Dan; Zong, Liang; Li, Daxue; Sui, Shaohui; Xiao, Yanhua; Zhuang, Bo; Shen, Yongling; Huang, Zhiping; Wu, Weihui
• Is Part Of: Journal of materials chemistry. Volume 11:Issue 12(2023)
• Page Start: 4025
• Page End: 4032
• Publication Date: 2023-03-13
• Subjects: Materials -- Periodicals; Chemistry, Analytic -- Periodicals; Optical materials -- Research -- Periodicals; Electronics -- Materials -- Research -- Periodicals; 543.0284
• DOI: 10.1039/d2tc05201f
• Languages: English
• ISSNs: 2050-7526

Abstract

Abstract : A salicylaldoximate-based AIE probe TPE-D successively undergoes the formation of nitrile and the phosphorylation of phenolic hydroxyl group when detecting DCP, which will give a significant fluorescence 'light-up' response within minutes. Abstract : Nerve agents are one of the most dangerous and toxic chemical warfare agents (CWAs). Their rapid detection is very important for specialized persons to take action against these substances. In this work, a salicylaldoximate-based aggregation-induced emission (AIE) probe, 2-hydroxy-5-(1, 2, 2-triphenylvinyl) benzoxime (TPE-D), was rationally designed for this purpose. The AIE fluorescent sensor has a tetraphenylethylene (TPE) unit combined with a salicylaldoximate moiety as the reaction site for a nerve agent simulant, diethyl chlorophosphate (DCP). TPE-D successively undergoes the formation of nitrile and the phosphorylation of a phenolic hydroxyl group after the salicylaldoximate moiety reacts with DCP, which will give a significant fluorescence "light-up" response due to the AIE effect within minutes.