2D Material‐Based Optical Biosensor: Status and Prospect. Issue 4 (13th December 2021)

• Record Type: Journal Article
• Authors: Lei, Zong‐Lin; Guo, Bo
• Is Part Of: Advanced science. Volume 9:Issue 4(2022)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2021-12-13
• Subjects: 2D materials -- evanescent wave -- fluorescence resonance energy transfer -- optical biosensor -- surface plasmon resonance; Science -- Periodicals; 505
• DOI: 10.1002/advs.202102924
• Languages: English
• ISSNs: 2198-3844

Abstract

Abstract: The combination of 2D materials and optical biosensors has become a hot research topic in recent years. Graphene, transition metal dichalcogenides, black phosphorus, MXenes, and other 2D materials (metal oxides and degenerate semiconductors) have unique optical properties and play a unique role in the detection of different biomolecules. Through the modification of 2D materials, optical biosensor has the advantages that traditional sensors (such as electrical sensing) do not have, and the sensitivity and detection limit are greatly improved. Here, optical biosensors based on different 2D materials are reviewed. First, various detection methods of biomolecules, including surface plasmon resonance (SPR), fluorescence resonance energy transfer (FRET), and evanescent wave and properties, preparation and integration strategies of 2D material, are introduced in detail. Second, various biosensors based on 2D materials are summarized. Furthermore, the applications of these optical biosensors in biological imaging, food safety, pollution prevention/control, and biological medicine are discussed. Finally, the future development of optical biosensors is prospected. It is believed that with their in‐depth research in the laboratory, optical biosensors will gradually become commercialized and improve people's quality of life in many aspects. Abstract : The combination of 2D materials and optical sensors has become a hot research topic in recent years. Here, the recent progress of optical biosensors based on various 2D materials (graphene, black phosphorus, and MXenes) is reviewed. Furthermore, the applications of these sensors in biological imaging, food safety, pollution prevention and biomedicine are discussed. Finally, their future development trend is prospected.