Assessment of Systemic Immune-inflammation Index Levels in Patients with Retinal Vein Occlusion. (16th March 2023)

• Record Type: Journal Article
• Authors: Zuo, Wen; Chen, Ting; Song, Jiayi; Ai, Ming
• Is Part Of: Ocular immunology and inflammation. Volume 31:Number 3(2023)
• Page Start: 491
• Page End: 495
• Publication Date: 2023-03-16
• Subjects: Systemic immune-inflammation index -- complete blood count -- retinal vein occlusion -- neutrophil-to-lymphocyte ratio -- platelet-to-lymphocyte ratio; Eye -- Diseases -- Immunological aspects -- Periodicals; Eye -- Inflammation -- Periodicals; 617.7
• DOI: 10.1080/09273948.2022.2032199
• Languages: English
• ISSNs: 0927-3948

Abstract

ABSTRACT: Purpose: To assess the predictive value of inflammatory markers calculated from complete blood counts in patients with retinal vein occlusion (RVO). Methods: This was a retrospective cross-sectional study with a total of 56 RVO patients and 56 age- and gender-matched controls involved. All subjects went through a routine ocular examination, and the peripheral venous blood samples were collected to analyze the differences in inflammatory markers between groups. Results: The systemic immune-inflammation index (SII) and neutrophil-to-lymphocyte ratio (NLR) values were significantly higher in RVO patients than those in the controls (p=0.002, p=0.004, respectively). According to the receiver operating characteristic (ROC) curve analysis, the areas under the curve (AUC) of SII was 0.666. The AUC of NLR was 0.657. Conclusion: As a novel inflammatory indicator, SII is a more promising indicator than NLR and PLR in the prediction of RVO development.