Differentiation of a Falcine Meningioma From Cerebral Venous Sinus Thrombosis Using DOTATATE PET. (8th May 2023)

• Record Type: Journal Article
• Authors: Stetter, Isabelle; Werner, Jan-Michael; Schroeter, Michael; Baumann, Claudia; Neuneier, Janina; Schlamann, Marc; Schmidt, Matthias; Drzezga, Alexander; Fink, Gereon R.; Galldiks, Norbert
• Is Part Of: Clinical nuclear medicine. Volume 48:Number 5(2023)
• Page Start: e235
• Page End: e236
• Publication Date: 2023-05-08
• Subjects: cerebral venous sinus thrombosis -- DOTATATE PET -- meningioma -- MRI; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000004594
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract: Differentiating brain tumors from nonneoplastic lesions using conventional MRI may be challenging. Clinical symptoms often remain unspecific, and imaging findings from MRI may be inconclusive. We present the case of a 23-year-old woman in whom an MRI suggested a cerebral venous sinus thrombosis. On the other hand, additional atypical MRI findings raised doubts regarding the initial diagnosis. Given the need for a diagnostic procedure with higher sensitivity and specificity for neoplastic tissue, PET with the radiolabeled somatostatin receptor ligand DOTATATE ( 68 Ga-DOTA-d -Phe1-Tyr3-octreotate) was performed. DOTATATE PET facilitated the diagnosis of a falcine meningioma consistent with its value for the differential diagnosis of meningioma.