Current laser therapy options for endoscopic treatment of upper tract urothelial carcinoma. (10th March 2023)

• Record Type: Journal Article
• Authors: Zollinger, Benjamin W.; Shoen, Ezra J.; Gresham, Charles F.; Whalen, Michael J.
• Is Part Of: Current urology. Volume 17:Number 1(2023)
• Page Start: 62
• Page End: 67
• Publication Date: 2023-03-10
• Subjects: Endoscopic management -- Holmium laser -- Laser ablation -- Thulium laser -- Upper tract urothelial carcinoma; Urology -- Periodicals; Genitourinary organs -- Surgery -- Periodicals; Genitourinary organs -- Diseases -- Periodicals; 616.6005
• DOI: 10.1097/CU9.0000000000000158
• Languages: English
• ISSNs: 1661-7649

Abstract

Abstract: Endoscopic management via retrograde ureteroscopic laser ablation of upper tract urothelial carcinoma (UTUC) has become the preferred treatment modality for low-risk tumors. The most popular ablative lasers over the past 15–20 years have been the holmium:yttrium-aluminum-garnet (Ho:YAG) and neodymium (Nd:YAG) lasers, but recently the thulium (Th:YAG) laser has emerged as a potential alternative. This review compares the mechanism of action, physiological properties and effects, and oncologic outcomes of Ho:YAG/Nd:YAG lasers versus the Th:YAG laser for UTUC treatment. Potential advantages of the Th:YAG laser over existing technologies are outlined, followed by a discussion of emerging laser technologies in UTUC management.