Histological Features Associated With Human Mpox Virus Infection in 2022 Outbreak in a Nonendemic Country. (1st November 2022)

• Record Type: Journal Article
• Authors: Chalali, Faris; Merlant, Marie; Truong, Audrey; Ghosn, Jade; Phung, Bao-Chau; Mollo, Bastien; Perrineau, Ségolène; Rahi, Mayda; Fidouh-Houhou, Nadhira; Ferré, Valentine Marie; Brunet-Possenti, Florence; Descamps, Vincent; Bouscarat, Fabrice; Yazdanpanah, Yazdan; Deschamps, Lydia; Bertin, Chloé
• Is Part Of: Clinical infectious diseases. Volume 76:Number 6(2023)
• Page Start: 1132
• Page End: 1135
• Publication Date: 2022-11-01
• Subjects: poxvirus -- monkeypox -- outbreak -- histology -- imaging; Communicable diseases -- Periodicals; 616.905
• DOI: 10.1093/cid/ciac856
• Languages: English
• ISSNs: 1058-4838

Abstract

Abstract: Skin histology of papules and pustules from 5 men having sex with men with mpox infection showed viral intracytoplasmic cytopathic changes, interface dermatitis, marked inflammatory dermic infiltrate including superficial neutrophils and perivascular and periadnexal deep lymphocytes. Histologic description of mpox lesions improves our understanding about clinical presentations and may have some therapeutic implications.