Successful treatment with ivabradine in a β‐blocker‐refractory patient with acute decompensated heart failure with reduced ejection fraction. Issue 3 (4th March 2023)

• Record Type: Journal Article
• Authors: Inoue, Tomoko; Matsunaga, Keiji; Kobayashi, Waki; Minamino, Tetsuo
• Is Part Of: Clinical case reports. Volume 11:Issue 3(2023)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2023-03-04
• Subjects: acute decompensated heart failure -- cancer therapy‐related cardiac dysfunction -- inappropriate tachycardia -- ivabradine -- up‐titration -- β‐Blocker; Medicine -- Periodicals; 616.09
• DOI: 10.1002/ccr3.6890
• Languages: English
• ISSNs: 2050-0904

Abstract

Abstract: Ivabradine is an established treatment for chronic heart failure with reduced ejection fraction (HFrEF); however, it is not used for acute heart failure treatment. Negative inotropic effects (NIE) often limit the up‐titration of β‐blockers. Contrarily, ivabradine has no NIE, and enables β‐blockers usage for treating patients with acute decompensated HFrEF. Abstract : Inappropriate tachycardia is a symptom of acute heart failure and is often dealt with β‐blockers. However, β‐blocker up‐titration is challenging because of its negative inotropic effects. Thus, ivabradine is preferable over β‐blockers in such cases.