Characteristics of Potential and Actual Living Kidney Donors: A Single-center Experience. Issue 4 (21st November 2022)

• Record Type: Journal Article
• Authors: Cholin, Liza K.; Schold, Jesse D.; Arrigain, Susana; Poggio, Emilio D.; Sedor, John R.; O'Toole, John F.; Augustine, Joshua J.; Wee, Alvin C.; Huml, Anne M.
• Is Part Of: Transplantation. Volume 107:Issue 4(2023)
• Page Start: 941
• Page End: 951
• Publication Date: 2022-11-21
• Subjects: Transplantation of organs, tissues, etc -- Periodicals; Transplantation immunology -- Periodicals; 617.95
• DOI: 10.1097/TP.0000000000004357
• Languages: English
• ISSNs: 0041-1337

Abstract

Abstract : Background: There are limited data and no national capture of barriers associated with initiating and completing the donation process for potential living kidney donors (LKDs). Methods: We performed a retrospective analysis of 3001 intake forms completed by prospective LKDs from 2016 to 2019 at a single transplant center. We analyzed data from all potential donors who completed the intake until they became ineligible or withdrew or donation was complete. We used univariate and multivariate models to evaluate independent factors associated with donation at various stages in the donation process. Results: The donation process was deconstructed into 5 steps: intake form, immunologic compatibility testing, clinic evaluation, selection committee review, and donation. The highest percentage of potential donors dropped out after completing the intake form, primarily because of not responding to the follow-up phone call (22.6%). Of 455 potential LKDs that completed immunologic compatibility testing, 36% were ABO or crossmatch incompatible. One-hundred eighty-eight (7.5%) of all LKD applicants reached donation, the majority of whom were White (91.0%) and female (63.8%). Conclusions: A minority of LKD applicants make it to donation. Our ability to track all potential LKDs from the initial touch point to the transplant center will help us develop interventions to address barriers to a successful donation. Abstract :