The Association Between Prebooster Vaccination Antibody Levels and the Risk of Severe Acute Respiratory Syndrome Coronavirus 2 Infection. (11th November 2022)

• Record Type: Journal Article
• Authors: Barda, Noam; Canetti, Michal; Gilboa, Mayan; Asraf, Keren; Indenboim, Victoria; Weiss-Ottolenghi, Yael; Amit, Sharon; Zubli, Daniel; Doolman, Ram; Mendelson, Ella; Freedman, Laurence S; Kreiss, Yitshak; Lustig, Yaniv; Regev-Yochay, Gili
• Is Part Of: Clinical infectious diseases. Volume 76:Number 7(2023)
• Page Start: 1315
• Page End: 1317
• Publication Date: 2022-11-11
• Subjects: SARS-CoV-2 -- mRNA vaccines -- boosters -- IgG levels -- infection risk; Communicable diseases -- Periodicals; 616.905
• DOI: 10.1093/cid/ciac886
• Languages: English
• ISSNs: 1058-4838

Abstract

Abstract: The correlation between anti–severe acute respiratory syndrome coronavirus 2 antibody levels and infection was reported. Here, we estimated the role of pre–fourth dose levels using data from 1098 healthcare workers. The risk of infection was reduced by 46% (95% confidence interval, 29%–59%) for each 10-fold increase in prebooster levels. Prebooster antibody levels could be used to optimally time boosters.