Multifocal Osteonecrosis in a 3-Year-old Child With Sickle Beta Plus Thalassemia. Issue 2 (March 2022)

• Record Type: Journal Article
• Authors: Bhasin, Neha; Price, Nathan; Desoky, Sarah M.
• Is Part Of: Journal of pediatric hematology/oncology. Volume 44:Issue 2(2022)
• Publication Date: 2022-03
• Subjects: sickle beta plus thalassemia -- multifocal osteonecrosis -- children; Pediatric hematology -- Periodicals; Tumors in children -- Periodicals; 618.9215
• DOI: 10.1097/MPH.0000000000002155
• Languages: English
• ISSNs: 1077-4114

Abstract

Abstract : Sickle beta+thalassemia is considered to be a mild form of sickle cell disease. However, some patients with mild disease can present with osteonecrosis. Here, we present a rare 3-year-old male who presented with acute pain, a baseline hemoglobin of 13 g/dL, who acutely developed multifocal osteonecrosis, and improved with partial exchange transfusion and hydroxyurea therapy.