Extremely premature infants with patent ductus arteriosus closure: Comparative analysis of surgical ligation versus cardiac catheterization-based closure. Issue 12 (25th March 2022)

• Record Type: Journal Article
• Authors: Pandey, Rajesh; Youmans, Lydia; Aneji, Chiamaka; Bell, Cynthia; Breinholt, John; Khan, Amir
• Other Names: Elshmaa Manal section editor.
• Is Part Of: Medicine. Volume 101:Issue 12(2022)
• Publication Date: 2022-03-25
• Subjects: catheter based closure of patent ductus arteriosus -- extremely low birth weight infant -- extremely premature infants -- hemodynamic decompensation after patent ductus arteriosus closure -- patent ductus arteriosus -- surgical ligation of patent ductus arteriosus; Medicine -- Periodicals; Medicine -- Periodicals; Médecine -- Périodiques; Geneeskunde; Medicine; Periodicals; Periodicals; 610.5
• DOI: 10.1097/MD.0000000000029103
• Languages: English
• ISSNs: 0025-7974

Abstract

Abstract : Abstract: Our objective was to compare postprocedure hemodynamic decompensation in extremely premature infants who had their patent ductus arteriosus (PDA) closed with surgical ligation (SL) versus cardiac catheter-based closure (CCC). This is a single-center retrospective review of extremely premature ( < 28 weeks) infants who had their PDA closed by SL or CCC. Of the total of 69 infants, 53 underwent SL, and 16 had CCC. Infants in 2 groups were comparable at birth. However, at the time of the procedure, infants in the SL group were smaller, less mature, and had higher respiratory support. Vasopressor use, both pre- and postprocedure, was more common in the SL group. Nineteen percent of the infants in the SL group, compared to 6% in the CCC group ( P = .34), required dose escalation or use of vasopressors after the PDA closure. There was no significant difference between the 2 groups in postoperative hemodynamic decompensation. Large, multicenter, prospective study or randomized control trial will help to confirm our findings.