The Use of a Dehydrated Complete Human Placental Membrane Allograft for Mohs Surgical Defects of the Nose. Issue 4 (13th April 2023)

• Record Type: Journal Article
• Authors: Wilmas, Kelly M.; Patel, Jigar; Silapunt, Sirunya; Doan, Hung Q.; Migden, Michael R.
• Is Part Of: Dermatologic surgery. Volume 49:Issue 4(2023)
• Page Start: 343
• Page End: 347
• Publication Date: 2023-04-13
• Subjects: Skin -- Surgery -- Periodicals; Skin -- Diseases -- Surgery -- Periodicals; 617.477
• DOI: 10.1097/DSS.0000000000003711
• Languages: English
• ISSNs: 1076-0512

Abstract

Abstract : BACKGROUND: Repair options for Mohs surgical defects include primary closure, flap or graft, or healing by second intention. These options may not be optimal in all cases. A dehydrated complete human placental membrane (dCHPM) allograft may serve as an alternative repair option. OBJECTIVE: To assess the aesthetic and functional outcomes of an alternative repair technique for Mohs surgical defects of the nose. METHODS: Twenty patients with Mohs surgical defects of the nose repaired with a dCHPM allograft were retrospectively identified. Photographs were used to demonstrate surgical technique and outcomes. Two blinded observers evaluated final outcomes using the Patient and Observer Scar Assessment Scale. RESULTS: Observers rated the scar outcome a combined mean score of 8.4 ± 3.2 (scale 5–50). Patients rated their outcomes a mean of 12.6 ± 7.4 (scale 6–60). The mean "Overall Opinion score" was 2.5 ± 1.8 by patients and 1.9 ± 1.3 by observers (scale 1–10). Limitations: This was a single institution study with a small sample size. CONCLUSION: Our study demonstrates that dCHPM allografts are a viable alternative repair option for Mohs surgical defects of the nose.