Acute coronary syndrome management in hemophiliacs: How to maintain balance?: A review. Issue 11 (17th March 2023)

• Record Type: Journal Article
• Authors: Chen, Hao; Yang, Shaning
• Is Part Of: Medicine. Volume 102:Issue 11(2023)
• Page Start: e33298
• Publication Date: 2023-03-17
• Subjects: acute coronary syndrome -- hemophilia -- hemophilia A -- hemophilia B; Medicine -- Periodicals; Medicine -- Periodicals; Médecine -- Périodiques; Geneeskunde; Medicine; Periodicals; Periodicals; 610.5
• DOI: 10.1097/MD.0000000000033298
• Languages: English
• ISSNs: 0025-7974

Abstract

Abstract : To analyze existing literature and understand how to balance the minimization of bleeding risk and ensuring adequate anticoagulation during coronary intervention treatment and long-term postoperative anticoagulation in hemophilia patients during the perioperative period, in order to provide guidance for healthcare professionals in developing effective treatment plans. This narrative review will analyze existing studies, case reports, and clinical guidelines to determine the most effective strategies for managing acute coronary syndrome in hemophilia patients. When evaluating the literature, factors such as patient age, medical history, and severity of the condition will be considered. The current management guidelines for acute coronary syndrome in hemophilia patients are not based on systematic evaluation and mainly rely on expert opinions. This article provides a comprehensive analysis of existing literature and recommends coagulation factor replacement therapy before anticoagulation and intervention treatment, as well as personalized anticoagulation treatment during the postoperative period for better management of hemophilia patients with acute coronary syndrome. These recommendations can help healthcare professionals develop more effective treatment plans for hemophilia patients.