Diagnosing nociplastic pain in cancer survivors: a major step forward. (May 2023)

• Record Type: Journal Article
• Authors: Verspyck, Emmanuel; Attal, Nadine
• Is Part Of: British journal of anaesthesia. Volume 130:Number 5(2023)
• Page Start: 515
• Page End: 518
• Publication Date: 2023-05
• Subjects: cancer pain -- central sensitisation -- fibromyalgia -- IDC-11 classification -- nociplastic pain -- pain modulation; Anesthesiology -- Periodicals; Anesthesia -- Periodicals; 617.9605
• DOI: 10.1016/j.bja.2023.02.006
• Languages: English
• ISSNs: 0007-0912

Abstract

Summary: Nociplastic pain syndromes include particular fibromyalgia, irritable bowel syndrome, headache, complex regional pain syndrome, and idiopathic orofacial pain. Several mechanisms have been proposed to account for nociplastic pain including central sensitisation, alterations of pain modulatory controls, epigenetic changes, and peripheral mechanisms. Importantly, nociplastic pain might also be present in patients with cancer pain, particularly those with pain related to complications of cancer treatment. Increased awareness of nociplastic pain associated with cancer should have important implications for monitoring and managing such patients.