Convergent synthesis of triarylamines via Ni-catalyzed dual C(sp2)–H amination from benzamides with benzohydroxamic acids. Issue 29 (22nd March 2023)

• Record Type: Journal Article
• Authors: Li, Wenwei; Wang, Ruxue; Li, Zhefeng; Chen, Jiuxi; Zhang, Yuhong; Lv, Ningning
• Is Part Of: Chemical communications. Volume 59:Issue 29(2023)
• Page Start: 4360
• Page End: 4363
• Publication Date: 2023-03-22
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/d3cc00165b
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : A nickel-catalyzed dual C(sp 2 )–H amination of N -quinolylbenzamides using broad-spectrum hydroxylamine as the amino source is developed for the selective synthesis of triarylamines in a single-step manner. Abstract : An unprecedented method of nickel-catalyzed dual C(sp 2 )–H amination of N -quinolylbenzamides with benzohydroxamic acids is developed to access triarylamines in one pot. For the first time, broad-spectrum hydroxylamine is employed as an amino source for C–H amination, featuring good chemo-selectivity and functional group tolerance. Furthermore, the catalytic system could be further extended to N -(pivaloyloxy)benzamide, dioxazolone, isocyanate and aniline for C–H amination.