Long-term weight loss outcome of laparoscopic Roux-en-Y gastric bypass predicted by weight loss at 6 months in Chinese patients with BMI ≥ 32.5 kg/m2. Issue 12 (24th March 2023)

• Record Type: Journal Article
• Authors: Wuyun, Qiqige; Wang, Dezhong; Tian, Chenxu; Xu, Guangzhong; Amin, Buhe; Lian, Dongbo; Du, Dexiao; Zhang, Weihua; Jiang, Min; Chen, Guanyang; Zhang, Nengwei; Wang, Liang
• Is Part Of: Medicine. Volume 102:Issue 12(2023)
• Page Start: e33235
• Publication Date: 2023-03-24
• Subjects: BMI ≥ 32.5 kg/m2 -- laparoscopic Roux-en-Y gastric bypass -- prognostic prediction -- weight loss; Medicine -- Periodicals; Medicine -- Periodicals; Médecine -- Périodiques; Geneeskunde; Medicine; Periodicals; Periodicals; 610.5
• DOI: 10.1097/MD.0000000000033235
• Languages: English
• ISSNs: 0025-7974

Abstract

Abstract : Laparoscopic Roux-en-Y gastric bypass (LRYGB) is classic bariatric procedure with long-term safety and efficacy. However, no studies have focused on predicting long-term weight loss after LRYGB in Chinese patients with body mass index (BMI) ≥ 32.5 kg/m 2 . To explore the relationship between initial and long-term weight loss after LRYGB in patients with BMI ≥ 32.5 kg/m 2 . All patients were followed-up to evaluate BMI, percentage of excess weight loss (%EWL), and comorbidities. Linear and logistic regression were performed to assess the relationship between initial and long-term weight loss. Receiver operating characteristic curve was used to determine optimal cutoff value. We enrolled 104 patients. The median preoperative BMI was 41.44 (37.92–47.53) kg/m 2 . %EWL ≥ 50% at 5 years was considered as successful weight loss, and 75.00% of the patients successfully lost weight. The cure rates of hypertension, hyperlipidemia, and type 2 diabetes mellitus at 1 year were 84.38%, 33.93%, and 60.82%, respectively. %EWL at 6 months and 5 years were positively correlated and its relationship could be described by following linear equation: %EWL5 years = 43.934 + 0.356 × %EWL6 months ( P < .001; r 2 = 0.166). The best cutoff %EWL at 6 months after LRYGB to predict 5-year successful weight loss was 63.93% (sensitivity, 53.85%; specificity, 84.62%; area under the curve (AUC) = 0.671). In Chinese patients with BMI ≥ 32.5 kg/m 2, %EWL at 6 months and 5 years were positively correlated and %EWL at 5 years could be calculated by following linear equation: %EWL5 years = 43.934 + 0.356 × %EWL6 months .