Association of rest-activity circadian rhythm with chronic respiratory diseases, a cross-section survey from NHANES 2011–2014. (April 2023)

• Record Type: Journal Article
• Authors: Gu, Wenbo; Tian, Zhen; Tian, Wei; Song, Yuhua; Qi, Guolian; Qi, Jiayue; Sun, Changhao
• Is Part Of: Respiratory medicine. Volume 209(2023)
• Publication Date: 2023-04
• Subjects: Rest-activity circadian rhythm -- Chronic respiratory diseases -- Emphysema -- Chronic bronchitis -- Asthma; Chest -- Diseases -- Periodicals; Chest -- Diseases -- Great Britain -- Periodicals; Respiratory organs -- Diseases -- Periodicals; Respiratory Tract Diseases -- Periodicals; Appareil respiratoire -- Maladies -- Périodiques; Thorax -- Maladies -- Périodiques; Appareil respiratoire -- Maladies -- Traitement -- Périodiques; Electronic journals; 616.2
• DOI: 10.1016/j.rmed.2023.107147
• Languages: English
• ISSNs: 0954-6111

Abstract

Abstract: Objective: A growing number of studies have examined the 24-h rest-activity characteristics in relation to health outcomes. Up to now, few studies have paid attention to the role of rest-activity circadian rhythm in chronic respiratory diseases (CRDs); therefore, to fill this gap, our study innovatively explored the association of rest-activity circadian rhythm indices with CRDs. Methods: A total of 7412 participants from the National Health and Nutrition Examination Survey (NHANES) 2011–2014 were included in this study. The rest-activity circadian rhythm indices were calculated using accelerometer data and were divided into quartiles to perform logistic regression. Results: Participants in the highest quartile of Relative amplitude (RA) had a lower prevalence of emphysema, chronic bronchitis and asthma, compared to those in the lowest quartile. Participants in the highest quartile of Intradaily variability (IV) was associated with a higher prevalence of emphysema relative to those in the lowest quartile. Compared to those in the lowest quartile, participants in the highest quartile of the average activity of the most active continuous 10-h period (M10) had a lower prevalence of emphysema. Additionally, compared to those in the lowest quartile of the average activity of the least active continuous 5-h period (L5) and L5 start time, participants in the highest quartile had a higher prevalence of asthma. Conclusions: This study demonstrated that in general US adult population, disrupted rest-activity circadian rhythm was associated with a higher prevalence of CRDs.