Fabrication of Smart Tantalum Carbide MXene Quantum Dots with Intrinsic Immunomodulatory Properties for Treatment of Allograft Vasculopathy (Adv. Funct. Mater. 46/2021). (10th November 2021)

• Record Type: Journal Article
• Authors: Rafieerad, Alireza; Yan, Weiang; Alagarsamy, Keshav Narayan; Srivastava, Abhay; Sareen, Niketa; Arora, Rakesh C.; Dhingra, Sanjiv
• Is Part Of: Advanced functional materials. Volume 31:Number 46(2021)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2021-11-10
• Subjects: allograft vasculopathy -- bioactive material -- hydrofluoric acid‐free synthesis -- in vivo immunomodulation -- Ta 4C 3Tx MXene quantum dots; Materials -- Periodicals; Chemical vapor deposition -- Periodicals; 620.11
• DOI: 10.1002/adfm.202170341
• Languages: English
• ISSNs: 1616-301X

Abstract

Abstract : Allograft Vasculopathy In article number 2106786, Sanjiv Dhingra and co‐workers demonstrate the development and application of immunoengineered tantalum‐carbide MXene quantum dots (MQDs) for the treatment of transplant vasculopathy. These MQDs are synthesized with high efficiency and purity using a hydrofluoric acid‐free protocol and are enriched with bioactive functional groups. The MQDs possess intrinsic immunomodulatory properties, are spontaneously uptaken into antigen‐presenting cells, and reduce activation of allogeneic T‐lymphocytes.