The blood–brain barrier—a metabolic ecosystem. (19th April 2022)
- Record Type:
- Journal Article
- Title:
- The blood–brain barrier—a metabolic ecosystem. (19th April 2022)
- Main Title:
- The blood–brain barrier—a metabolic ecosystem
- Authors:
- Castro, Marco
Potente, Michael - Abstract:
- Abstract : A functional blood–brain barrier relies on a tightly controlled interplay between endothelial cells, pericytes, and astrocytes, which together form the neurovascular unit. Recent work by Lee et al (2022) discovers endothelial cell‐derived lactate as a crucial metabolic fuel for brain pericytes, revealing a new way of CNS vascular communication that links nutrient metabolism to blood–brain barrier function. Abstract : Recent work reports a key role for lactate exchange between endothelial cells and neurovascular pericytes in support of brain vasculature integrity.
- Is Part Of:
- EMBO journal. Volume 41:Number 9(2022)
- Journal:
- EMBO journal
- Issue:
- Volume 41:Number 9(2022)
- Issue Display:
- Volume 41, Issue 9 (2022)
- Year:
- 2022
- Volume:
- 41
- Issue:
- 9
- Issue Sort Value:
- 2022-0041-0009-0000
- Page Start:
- n/a
- Page End:
- n/a
- Publication Date:
- 2022-04-19
- Subjects:
- Molecular biology -- Periodicals
572.805 - Journal URLs:
- http://onlinelibrary.wiley.com/ ↗
- DOI:
- 10.15252/embj.2022111189 ↗
- Languages:
- English
- ISSNs:
- 0261-4189
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3733.085000
British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 26777.xml