3D Bioprinting of Engineered Tissue Flaps with Hierarchical Vessel Networks (VesselNet) for Direct Host‐To‐Implant Perfusion (Adv. Mater. 42/2021). Issue 42 (19th October 2021)

• Record Type: Journal Article
• Authors: Szklanny, Ariel A.; Machour, Majd; Redenski, Idan; Chochola, Václav; Goldfracht, Idit; Kaplan, Ben; Epshtein, Mark; Simaan Yameen, Haneen; Merdler, Uri; Feinberg, Adam; Seliktar, Dror; Korin, Netanel; Jaroš, Josef; Levenberg, Shulamit
• Is Part Of: Advanced materials. Volume 33:Issue 42(2021)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2021-10-19
• Subjects: 3D bioprinting -- ECM bioink -- engineered flap -- personalized medicine -- tissue engineering -- vascularization; Materials -- Periodicals; Chemical vapor deposition -- Periodicals; 620.11
• DOI: 10.1002/adma.202170335
• Languages: English
• ISSNs: 0935-9648

Abstract

Abstract : 3D Bioprinting Millimetric tubular scaffolds and 3D bioprinted vascularized collagen hydrogels are combined by Shulamit Levenberg and co‐workers in article number 2102661 to create engineered hierarchically vascularized tissues (engineered flap) consisting of rich microvascular networks in communication with an engineered endothelium. The in vitro cultured flaps are directly anastomosed to the host vasculature, successfully perfusing the implanted tissue. This work represents a step forward to achieving large fully engineered human tissues.