Spindle cell tumour with thymus‐like differentiation (SETTLE) on fine needle aspiration cytology: A case report highlighting diagnostic pitfalls. Issue 8 (1st April 2021) - Adegun, Oluyori K.
Abstract: A 7‐year‐old girl presented with a painless neck swelling localised near the left lobe of the thyroid gland, which was initially investigated by fine needle aspiration cytology. This raised a differential diagnosis of medullary thyroid carcinoma and small round blue cell tumour. Only after several additional clinical investigations and a total thyroidectomy was a definitive diagnosis of spindle cell tumour with thymus‐like differentiation (SETTLE) reached. This case report highlights how contemporaneous clinical and investigation findings made arriving at a definitive diagnosis challenging, contributed to diagnostic delay, and ultimately influenced choice of treatment.