Aptamer-based proximity labeling guides covalent RNA modification. Issue 28 (10th March 2021)
- Record Type:
- Journal Article
- Title:
- Aptamer-based proximity labeling guides covalent RNA modification. Issue 28 (10th March 2021)
- Main Title:
- Aptamer-based proximity labeling guides covalent RNA modification
- Authors:
- Englert, Daniel
Matveeva, Regina
Sunbul, Murat
Wombacher, Richard
Jäschke, Andres - Abstract:
- Abstract : An aptamer-based proximity-induced inverse electron demand Diels–Alder reaction for fluorescent modification of RNAs is described. Abstract : We describe the development of a proximity-induced bio-orthogonal inverse electron demand Diels–Alder reaction that exploits the high-affinity interaction between a dienophile-modified RhoBAST aptamer and its tetramethyl rhodamine methyltetrazine substrate. We applied this concept for covalent RNA labeling in proof-of-principle experiments.
- Is Part Of:
- Chemical communications. Volume 57:Issue 28(2021)
- Journal:
- Chemical communications
- Issue:
- Volume 57:Issue 28(2021)
- Issue Display:
- Volume 57, Issue 28 (2021)
- Year:
- 2021
- Volume:
- 57
- Issue:
- 28
- Issue Sort Value:
- 2021-0057-0028-0000
- Page Start:
- 3480
- Page End:
- 3483
- Publication Date:
- 2021-03-10
- Subjects:
- Chemistry -- Periodicals
540 - Journal URLs:
- http://pubs.rsc.org/en/journals/journalissues/cc ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/d1cc00786f ↗
- Languages:
- English
- ISSNs:
- 1359-7345
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3139.350000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 26748.xml