A facile chemoenzymatic synthesis of SARS-CoV-2 glycopeptides for probing glycosylation functions. Issue 55 (18th June 2021)
- Record Type:
- Journal Article
- Title:
- A facile chemoenzymatic synthesis of SARS-CoV-2 glycopeptides for probing glycosylation functions. Issue 55 (18th June 2021)
- Main Title:
- A facile chemoenzymatic synthesis of SARS-CoV-2 glycopeptides for probing glycosylation functions
- Authors:
- Zong, Guanghui
Li, Chao
Prabhu, Sunaina Kiran
Zhang, Roushu
Zhang, Xiao
Wang, Lai-Xi - Abstract:
- Abstract : Structurally well-defined synthetic SARS-CoV-2 glycopeptides provide useful probes for characterizing the glycan binding specificity of lectin and neutralizing antibody. Abstract : Glycosylation plays important roles in SARS-CoV-2 infection. We describe here a facile chemoenzymatic synthesis of core-fucosylated N -glycopeptides derived from the SARS-CoV-2 Spike protein and their binding with glycan-dependent neutralizing antibody S309 and human lectin CLEC4G. The synthetic glycopeptides provide tools for further functional characterization of viral glycosylation.
- Is Part Of:
- Chemical communications. Volume 57:Issue 55(2021)
- Journal:
- Chemical communications
- Issue:
- Volume 57:Issue 55(2021)
- Issue Display:
- Volume 57, Issue 55 (2021)
- Year:
- 2021
- Volume:
- 57
- Issue:
- 55
- Issue Sort Value:
- 2021-0057-0055-0000
- Page Start:
- 6804
- Page End:
- 6807
- Publication Date:
- 2021-06-18
- Subjects:
- Chemistry -- Periodicals
540 - Journal URLs:
- http://pubs.rsc.org/en/journals/journalissues/cc ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/d1cc02790e ↗
- Languages:
- English
- ISSNs:
- 1359-7345
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3139.350000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 26749.xml