Co(iii)-catalysed regioselective linear C(8)–H olefination of isoquinolone with terminal aromatic and aliphatic alkynes. Issue 88 (12th October 2021) - Chandra, Devesh
Abstract : A regioselective C8 linear olefination of isoquinoline-1 H -2-one with terminal (aromatic and aliphatic) alkynes is reported under Co(iii ) catalysis. Abstract : A regioselective C8 linear olefination of isoquinoline-1 H -2-one with terminal (aromatic and aliphatic) alkynes is reported under Co(iii ) catalysis. This is an exclusive report on the C8 functionalization of isoquinolone using non-noble transition metal complexes. Experimental and computational mechanistic studies have also been performed to depict the reaction pathway.