ViralVacDB: A manually curated repository of viral vaccines. Issue 4 (April 2023)

• Record Type: Journal Article
• Authors: Tripathi, Sadhana; Sharma, Neelam; Naorem, Leimarembi Devi; Raghava, Gajendra P.S.
• Is Part Of: Drug discovery today. Volume 28:Issue 4(2023)
• Publication Date: 2023-04
• Subjects: virus -- vaccines -- viral diseases -- database -- approved vaccines -- clinical trials; Drugs -- Design -- Periodicals; Drugs -- Research -- Periodicals; 615.1
• DOI: 10.1016/j.drudis.2023.103523
• Languages: English
• ISSNs: 1359-6446

Abstract

Highlights: Compilation of vaccines against 26 major human diseases caused by viruses. A total of 422 viral vaccines (145 approved and 277 in clinical trials) is summarized. Comprehensive information of 214 vaccine records for COVID-19 disease is provided. Various routes of administration of the vaccines are discussed. A knowledgebase: ViralVacDB, provides in-depth information on viral vaccines. Abstract : Over the years, numerous vaccines have been developed against viral infections; however, a complete database that provides comprehensive information on viral vaccines has been lacking. In this review, along with our freely accessible database ViralVacDB, we provide details of the viral vaccines, their type, routes of administration and approving agencies. This repository systematically covers additional information such as disease name, adjuvant, manufacturer, clinical status, age and dosage against 422 viral vaccines, including 145 approved vaccines and 277 in clinical trials. We anticipate that this database will be highly beneficial to researchers and others working in pharmaceuticals and immuno-informatics.