TCR sequencing: applications in immuno-oncology research. (March 2023) - Sanromán, Á.F.
Highlights: T-cell receptor (TCR) interaction with major histocompatibility complex–antigen complexes leads to antitumour responses. TCR sequencing analysis allows characterisation of T cells that recognise tumour neoantigens. T-cell clonal revival and clonal replacement potentially underpin immunotherapy responses.