122 Defining Factors Predictive of Persistent Climacturia after Radical Prostatectomy. (1st May 2022)
- Record Type:
- Journal Article
- Title:
- 122 Defining Factors Predictive of Persistent Climacturia after Radical Prostatectomy. (1st May 2022)
- Main Title:
- 122 Defining Factors Predictive of Persistent Climacturia after Radical Prostatectomy
- Authors:
- Martinez, J Flores
Benfante, N
Schofield, E
Mulhall, JP - Abstract:
- ABSTRACT: Introduction: Climacturia (Cl) is defined as the involuntary leakage of urine around the time of orgasm. Cl is a common clinical condition after radical prostatectomy (RP). Cl is a barrier to sexual satisfaction. Rates as high as 60% have been reported with little data on the chronology of recovery. Objective: This study aimed to evaluate the natural history of CI after RP. Methods: Men who underwent RP and completed a proprietary sexual incontinence questionnaire at 12 and 24 months (±3 months) constituted the study sample. Pre or postop ADT or radiation therapy were exclusions. We assessed demographics, comorbidities, baseline testosterone (T), pre-RP prostate specific antigen (PSA), Gleason group, nerve sparing status (NSS), and the presence of stress urinary incontinence (SUI) post-RP. Primary end-point was Cl rate at 12 and 24 months post-RP. Predictors of Cl were analyzed using a series of logistic regression models. Factors entered into the model included age, diabetes, smoking history, baseline T, baseline PSA, Gleason score sum, and NSS score. Results: Data on 152 men were analyzed. Mean age 61±8 years. 45% had hypertension, 60% hyperlipidemia, 10% had diabetes, 18% obstructive sleep apnea, 8% were current smoker, and 27% former smokers. Baseline T and PSA were 421±176 ng/dL and 7±6 ng/mL. The median Gleason score was 7, 82% of patients had bilateral NSS, 13% unilateral. Median NSS score was 3 (IQR 2, 4). Cl prevalence at 12 and 24 months post-surgery wereABSTRACT: Introduction: Climacturia (Cl) is defined as the involuntary leakage of urine around the time of orgasm. Cl is a common clinical condition after radical prostatectomy (RP). Cl is a barrier to sexual satisfaction. Rates as high as 60% have been reported with little data on the chronology of recovery. Objective: This study aimed to evaluate the natural history of CI after RP. Methods: Men who underwent RP and completed a proprietary sexual incontinence questionnaire at 12 and 24 months (±3 months) constituted the study sample. Pre or postop ADT or radiation therapy were exclusions. We assessed demographics, comorbidities, baseline testosterone (T), pre-RP prostate specific antigen (PSA), Gleason group, nerve sparing status (NSS), and the presence of stress urinary incontinence (SUI) post-RP. Primary end-point was Cl rate at 12 and 24 months post-RP. Predictors of Cl were analyzed using a series of logistic regression models. Factors entered into the model included age, diabetes, smoking history, baseline T, baseline PSA, Gleason score sum, and NSS score. Results: Data on 152 men were analyzed. Mean age 61±8 years. 45% had hypertension, 60% hyperlipidemia, 10% had diabetes, 18% obstructive sleep apnea, 8% were current smoker, and 27% former smokers. Baseline T and PSA were 421±176 ng/dL and 7±6 ng/mL. The median Gleason score was 7, 82% of patients had bilateral NSS, 13% unilateral. Median NSS score was 3 (IQR 2, 4). Cl prevalence at 12 and 24 months post-surgery were 38% and 39%. No patient characteristics were associated with CI at either 12 or 24 months post-RP. Conclusion: Cl is highly prevalent at 12 months post RP and when present at this juncture appears to be unlikely to recover. Disclosure: Work supported by industry: no. … (more)
- Is Part Of:
- Journal of sexual medicine. Volume 19(2022)Supplement 2
- Journal:
- Journal of sexual medicine
- Issue:
- Volume 19(2022)Supplement 2
- Issue Display:
- Volume 19, Issue 2 (2022)
- Year:
- 2022
- Volume:
- 19
- Issue:
- 2
- Issue Sort Value:
- 2022-0019-0002-0000
- Page Start:
- S174
- Page End:
- S174
- Publication Date:
- 2022-05-01
- Subjects:
- Sexual disorders -- Periodicals
Sex -- Periodicals
Sexual health -- Periodicals
616.69005 - Journal URLs:
- http://firstsearch.oclc.org ↗
http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1743-6109 ↗
http://www.blackwell-synergy.com/openurl?genre=journal&eissn=1743-6109 ↗
http://www.blackwell-synergy.com/servlet/useragent?func=showIssues&code=jsm ↗
https://academic.oup.com/jsm ↗
http://onlinelibrary.wiley.com/ ↗ - DOI:
- 10.1016/j.jsxm.2022.03.395 ↗
- Languages:
- English
- ISSNs:
- 1743-6095
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 5064.060000
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