A comparative study into the effects of venous and arterial blood on clot microstructure in critically unwell patients. Assessment of the diagnostic potential of a biomarker of haemostasis. (May 2023) - Pillai, Suresh
Blood for coagulation analysis can be sampled from the arterial or venous system in intensive care units (ICU). The determination of clot microstructure and strength by fractal analysis (d f ) gives valuable information in a range of vascular haemostatic disease and sepsis. We aimed to determine if d f could be measured equally and comparatively in arterial or venous blood, and 45 critically ill patients in an ICU were recruited. d f was found to be readily measured in arterial blood with results comparable to those in venous blood and that add value of d f as a potential marker of haemostasis in these patients.