Comparative Evaluation of Seven Commercial Tests for Detection of Heterophile Antibody in Infectious Mononucleosis. (1992)

• Record Type: Journal Article
• Authors: Skulnick, Martin; Low, Donald E; Simor, Andrew E; Patel, Mohan; George, Pauline; Chua, Robert
• Is Part Of: Canadian Journal of Infectious Diseases. Volume 3:Number 1(1992)
• Page Start: 23
• Page End: 26
• Publication Date: 1992
• Subjects: Epstein-Barr virus -- Heterophile antibodies -- Infectious mononucleosis
• DOI: 10.1155/1992/510261
• Languages: English
• ISSNs: 1180-2332

Abstract

Abstract : Detection of heterophile antibodies in infectious mononucleosis is the most rapid and cost-effective method for confirming the clinical diagnosis of the disease. This study compared seven commercial test kits (the Oxoid Infectious Mononucleosis Kit [Oxoid Ltd], Immunoscan Im-Latex [Baxter Travenol], Mono-Latex [Wampole Laboratories], Monospot and Im Screen Test [Ortho Diagnostics], Immunoscan Im-RBC Test [Baxter Travenol], and Infectious Mononucleosis Test [NCS Diagnostics]) to the Davidsohn differential test. All of the kits were shown to be acceptable for use, with specificities and sensitivities greater than 96.5% and 95.5%, respectively.