A Computational Model for Biological Tissues Considering the Influence of Injury on Growth and Remodelling. Issue 1 (18th November 2019)

• Record Type: Journal Article
• Authors: Gierig, Meike; Marino, Michele; Wriggers, Peter
• Other Names: Eberhardsteiner J. guestEditor.; Schöberl M. guestEditor.
• Is Part Of: Proceedings in applied mathematics and mechanics. Volume 19:Issue 1(2019)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2019-11-18
• Subjects: Applied mathematics -- Periodicals; Engineering mathematics -- Periodicals; Mathematical physics -- Periodicals; 519
• DOI: 10.1002/pamm.201900259
• Languages: English
• ISSNs: 1617-7061

Abstract

Abstract: Biological tissues adapt to changed loading conditions through growth and remodelling (G&R) to reestablish a so‐called homeostatic state. On the other hand, loading conditions above their physiological limits, as during trauma or surgical procedures, cause injury and can initiate pathological G&R. Herein, a modelling approach for G&R influenced by injury is presented combining the theories of plasticity and homogenised constrained mixtures. The results show that injury has a significant impact on the G&R behaviour and thus on the accomplishment of homeostasis.