Angioscopic findings one year after percutaneous coronary intervention for chronic total occlusion. (25th November 2020)

• Record Type: Journal Article
• Authors: Fukuizumi, I.F; Tokita, Y.T; Mozawa, K.M; Sasamoto, N.S; Seki, T.S; Wakita, M.W; Shiomura, R.S; Noma, S.N; Matsuda, J.M; Kubota, Y.K; Nakata, J.N; Tara, S.T; Yamamoto, T.Y; Takano, H.T; Shimizu, W.S
• Is Part Of: European heart journal. Volume 41:(2020)Supplement 2
• Publication Date: 2020-11-25
• Subjects: Coronary Angiography; Cardiology -- Periodicals; Heart -- Diseases -- Periodicals; 616.12005
• DOI: 10.1093/ehjci/ehaa946.2452
• Languages: English
• ISSNs: 0195-668X

Abstract

Abstract: Background: Chronic total occlusion (CTO) is thought as a high-risk feature of stent thrombosis, but little is known about the difference in neointimal healing of stents implanted for CTO lesions compared to that of non-CTO lesions. Methods and results: A total of 62 stents in consecutive 47 patients (69±11 years, 41 male) who underwent follow-up angiography and angioscopy one year after percutaneous coronary intervention (PCI) between March 2016 and July 2019 were evaluated. The examined stents were divided into 3 groups according to the lesion status at previous PCI: CTO group (n=12), stable coronary artery disease without CTO (non-CTO group, n=30) and acute coronary syndrome (ACS group, n=20). The grade of neointimal stent coverage in CTO group was significantly lower than that of non-CTO group (0.5±0.5 vs 1.4±0.9, p=0.001). The frequency of presence of thrombus was significantly higher in CTO group and ACS group compared to non-CTO group (67%, 50%, and 13%, respectively, p=0.001). The yellow grade in CTO group was equivalent (p=1.00) to that in ACS group and was tented to be higher (p=0.051) compared to non-CTO group (1.3±0.8, 1.5±0.6, and 0.8±0.7, respectively). Conclusion: The present study suggested a delayed healing in stents implanted for CTO lesions. Longer dual-antithrombotic therapy maybe beneficial for these patients. Funding Acknowledgement: Type of funding source: None