Endogenous Creatinine Clearance as a Clinical Measure of Glomerular Filtration Rate. Issue 5779 (9th October 1971)

• Record Type: Journal Article
• Authors: Bennett, William M.; Porter, George A.
• Is Part Of: BMJ. Volume 4:Issue 5779(1971)
• Page Start: 84
• Page End: 86
• Publication Date: 1971-10-09
• Subjects: Medicine -- Periodicals; Medicine -- Periodicals; Medicine; Periodicals; 610
• DOI: 10.1136/bmj.4.5779.84
• Languages: English
• ISSNs: 0007-1447

Abstract

Abstract : Endogenous creatinine clearance was assessed by inulin in 91 simultaneous studies in 41 patients and proved an accurate measurement of glomerular filtration rate. For filtration rates <20 ml/min the creatinine clearance may slightly overestimate the glomerular filtration rate. Successive determinations of filtration rate by either method may vary by 20% even though the methods agree with each other. Glomerular filtration rate itself is variable, and in its clinical usage this should be recognized.