Neonatal Hyperthyroidism and Long-acting Thyroid Stimulator Protector. Issue 5946 (21st December 1974)

• Record Type: Journal Article
• Authors: Nutt, J.; Clark, F.; Welch, R. G.; Hall, R.
• Is Part Of: BMJ. Volume 4:Issue 5946(1974)
• Page Start: 695
• Page End: 696
• Publication Date: 1974-12-21
• Subjects: Medicine -- Periodicals; Medicine -- Periodicals; Medicine; Periodicals; 610
• DOI: 10.1136/bmj.4.5946.695
• Languages: English
• ISSNs: 0007-1447

Abstract

Abstract : Neonatal hyperthyroidism has been thought to result from transplacental passage of long-acting thyroid stimulator (L.A.T.S.) from a mother with Graves's disease. A case is presented here in which no L.A.T.S. was detected in the mother or neonate but another immunoglobulin, L.A.T.S. protector, a specific human thyroid stimulator, was shown to be present in the mother's serum. This stimulator may have been the cause of the neonatal hyperthyroidism.