Activity Regulating Strategies of Nanozymes for Biomedical Applications. Issue 11 (17th January 2023)

• Record Type: Journal Article
• Authors: Ding, Xiaoteng; Zhao, Zhen; Zhang, Yanfang; Duan, Meilin; Liu, Chengzhen; Xu, Yuanhong
• Is Part Of: Small. Volume 19:Issue 11(2023)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2023-01-17
• Subjects: biomedical -- catalytic activity -- nanozymes -- regulation strategy; Nanotechnology -- Periodicals; Nanoparticles -- Periodicals; Microtechnology -- Periodicals; 620.5
• DOI: 10.1002/smll.202207142
• Languages: English
• ISSNs: 1613-6810

Abstract

Abstract: On accounts of the advantages of inherent high stability, ease of preparation and superior catalytic activities, nanozymes have attracted tremendous potential in diverse biomedical applications as alternatives to natural enzymes. Optimizing the activity of nanozymes is significant for widening and boosting the applications into practical level. As the research of the catalytic activity regulation strategies of nanozymes is boosting, it is essential to timely review, summarize, and analyze the advances in structure–activity relationships for further inspiring ingenious research into this prosperous area. Herein, the activity regulation methods of nanozymes in the recent 5 years are systematically summarized, including size and morphology, doping, vacancy, surface modification, and hybridization, followed by a discussion of the latest biomedical applications consisting of biosensing, antibacterial, and tumor therapy. Finally, the challenges and opportunities in this rapidly developing field is presented for inspiring more and more research into this infant yet promising area. Abstract : Nanozymes have attracted much attention in recent years. Optimizing the activity of nanozymes is significant for widening the biomedical applications. Herein, the various regulation strategies of nanozymes activity are summarized, including size and morphology, doping, vacancy, surface modification, and hybridization. The promising biomedical applications of nanozymes in biosensing, antibacterial, and tumor therapy are discussed in detail.