Sex, racial/ethnic and socioeconomic disparities in patients with metastatic bone disease. Issue 4 (10th December 2021)

• Record Type: Journal Article
• Authors: Jawad, Muhammad Umar; Pollock, Brad H.; Wise, Barton L.; Zeitlinger, Lauren N.; O' Donnell, Edmond F.; Carr‐Ascher, Janai R.; Cizik, Amy; Ferrell, Betty; Thorpe, Steven W.; Randall, R. Lor
• Is Part Of: Journal of surgical oncology. Volume 125:Issue 4(2022)
• Page Start: 766
• Page End: 774
• Publication Date: 2021-12-10
• Subjects: bone -- dispartiy -- metastasis; Cancer -- Surgery -- Periodicals; Neoplasms -- Periodicals; 616
• DOI: 10.1002/jso.26765
• Languages: English
• ISSNs: 0022-4790

Abstract

Abstract: Background: We have analyzed sex, race/ethnicity or socioeconomic disparities in the incidence of metastatic bone disease (MBD). Methods: Patients with the diagnosis of MBD at presentation for five most common primary anatomical sites was extracted from Surveillance, Epidemiology, and End Results Census tract–level dataset. Mean incidence of MBD for different sex, racial/ethnic and socioeconomic groups were compared. Results: The five most common anatomical sites with MBD at presentation include "lung: ( n = 59 739), "prostate" ( n = 19 732), "breast" ( n = 16 244), "renal" ( n = 7718) and "colon" ( n = 3068). There was an increase in incidence of MBD among cancers originating from prostate (annual percentage change [APC] 4.94), renal (APC 2.55), and colon (APC 3.21) ( p < 0.05 for all). Non‐Hispanic Blacks had higher incidence of MBD for prostate and breast primary sites ( p < 0.001). Non‐Hispanic American Indian Alaskan Native had higher incidence of MBD for cancers originating from renal ( p < 0.001) and colon ( p = 0.049). A higher incidence of MBD was seen in lower socioeconomic status (SES) groups for the selected sites ( p < 0.001). Conclusions: These findings suggest that there are multiple sex‐related, racial/ethnic and SES disparities in the incidence of MBD from the 5 most common primary sites. Higher incidence seen among lower SES suggests delay in diagnosis and limited access to screening modalities.