Relationship between cortical and medullary thickness and glomerular filtration rate among living kidney donors. Issue 3 (15th March 2023)

• Record Type: Journal Article
• Authors: Kuhnel, Lukas; Vu, Thomas; Wood, Simon T.; Francis, Ross S.; Trnka, Peter; Ellis, Robert J.
• Is Part Of: Internal medicine journal. Volume 53:Issue 3(2023)
• Page Start: 431
• Page End: 435
• Publication Date: 2023-03-15
• Subjects: living kidney donor -- glomerular filtration rate -- kidney cortex -- kidney medulla; Medicine -- Periodicals; 616
• DOI: 10.1111/imj.16033
• Languages: English
• ISSNs: 1444-0903

Abstract

Abstract: The relationship between the kidney cortex and medulla is not well understood in healthy populations. This study characterised the relationship between cortical/medullary thickness and measured glomerular filtration rate (GFR) in 390 living kidney donors. A positive relationship was observed between medullary, but not cortical, thickness and GFR. We propose that this reflects a correlation between juxtamedullary nephron number and GFR.